National Center for Complementary and Alternative Medicine (NCCAM)

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Botanical Estrogens: Mechanisms, Dose and Target Tissues

Principal Investigator: 
William Helferich, Ph.D.
University of Illinois-Urbana-Champaign, Champaign, IL


Office of Sponsored Programs & Research
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Champaign, IL 61820-7406
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This center will address the safety, efficacy, and mechanism of action of botanical estrogens (e.g., wild yam, soy, dong quai) consumed by women. The center's projects will look at the biological effects of botanical estrogens on molecular mechanisms and cellular pathways, as well as their actions on bone, uterus, breast tissue, breast cancer metastasis, and cognition.

Centers for Dietary Supplements Research: Botanicals