This page is an historical document and contains content that may be out of date.
Research Roundup
"Research Roundup" presents examples of NCCAM-funded research recently published in peer-reviewed journals listed in the National Library of Medicine's PubMed database.
Saw Palmetto for BPH
© Larry Allain, USGS-NWRC
Benign prostatic hyperplasia (BPH), also known as enlargement of the prostate, is a common complaint among older men. A plant called saw palmetto (Serenoa repens) is a popular CAM treatment for it. Researchers at the Osher Center for Integrative Medicine at the University of California, San Francisco, led by Stephen Bent, M.D., conducted a year-long clinical trial on the effects of saw palmetto on lower-urinary-tract symptoms of BPH. Two hundred and twenty-five men older than age 49 who had moderate-to-severe symptoms of BPH were randomized to receive either saw palmetto extract or a placebo. The investigators found no significant difference in symptoms or other outcome measures between the saw palmetto and placebo groups. The extract was generally well tolerated. The report appeared in the February 9, 2006, issue of the New England Journal of Medicine.
Yoga for Chronic Low-Back Pain
© Krzysztof Chrystowski
Chronic low-back pain (LBP) is a common reason that people seek medical care. Calling current treatment options "only modestly effective," Karen Sherman, Ph.D., M.P.H., and colleagues of the Group Health Cooperative in Seattle conducted a study of yoga (a mind-body therapy that involves both physical exercise and mental focus) for LBP. They chose the style of yoga called viniyoga, noting that some other styles may be inappropriate for back pain. Yoga was compared with two other treatments: therapeutic exercise classes and reading a self-help book. The three groups had 101 participants in total. Those in the yoga and exercise groups participated in instructor-led classes for 12 weeks and continued to practice on their own for 14 more weeks. At the end of the first 12 weeks, the LBP symptoms of all three groups had improved. Over the last 14 weeks, however, symptoms continued to improve in the yoga group only; symptoms in the other groups worsened.
The authors found that viniyoga is a safe and effective treatment for chronic LBP. The study appeared in the December 20, 2005, issue of the Annals of Internal Medicine.
Could Meditation Help Age-Related Mental Decline?
The cerebral cortex of the brain is involved in many complex functions, such as thought, sensory perception, language, and emotion. It thins with age, and some scientists think this may be a factor in age-related mental decline. An article in the November 28, 2005, issue of NeuroReport describes a preliminary study of the cortical (i.e., cortex) thickness in 20 adults who practice a type of meditation called Buddhist Insight Meditation. The researchers, led by Sara Lazar, Ph.D., of Massachusetts General Hospital, also studied a control group of 15 participants who had no meditation or yoga experience. The researchers found that cortical regions responsible for attention and sensory processing (such as auditory and visual) were thicker in meditators than in controls. In older participants (aged 40 to 50 years), only the meditators showed cortical thickness that corresponded to that of younger participants (aged 20 to 30 years) in a region that carries out higher mental, emotional, and behavioral functions.
The authors concluded that meditating regularly may change the brain's structure in ways that are important to some mental functions and could help slow declines related to aging.
For more findings, see the NCCAM Grantee Publications Database. Sorting by "Publication Date" yields the most recent records first.
