National Center for Complementary and Alternative Medicine (NCCAM)

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2008 Meetings and Workshops

NIH Summit: The Science of Eliminating Health Disparities

Date: Tuesday, December 16, 2008 to Thursday, December 18, 2008

The National Center on Minority Health and Health Disparities will sponsor a summit to showcase the collective contribution of the NIH in the development of new knowledge in the Science of Eliminating Health Disparities.

Building the NIH Toolbox: Research in Cognition, Sensation, Emotion and Motor Function

Date: Monday, October 27, 2008

The NIH Toolbox initiative seeks to assemble brief, comprehensive assessment tools that will be useful to clinicians and researchers in a variety of settings, with a particular emphasis on measuring outcomes in longitudinal epidemiologic studies and prevention or intervention trials across the lifespan. Join the inaugural conference where there will be discussions on:

  • Introduction to the Toolbox and the NIH Blueprint
  • What Toolbox Promises
  • Toolbox Domains

Meditation for Health Purposes Workshop

Date: Tuesday, July 8, 2008 to Wednesday, July 9, 2008

Bethesda Maryland

Executive Summary

On July 8–9, 2008, the National Center for Complementary and Alternative Medicine (NCCAM) of the National Institutes of Health (NIH) held a 2-day workshop in Bethesda, Maryland on meditation for health purposes. It was co-sponsored by the National Cancer Institute (NCI), the National Institute on Aging (NIA), the NIH Office of Behavioral and Social Sciences (OBSSR), and the Canadian Institutes of Health Research (INMHA, ICRH). The purpose of the meeting was to articulate potential goals and directions for research on the mechanisms and efficacy of meditation practices for a variety of health concerns. Experts from a range of disciplines and with a wide range of involvement in the field of meditation research were asked to critically examine the current state of science on meditation for health, and to identify existing or potential intersections and contributions from their fields to further this area of science. This group developed a set of critical questions and approaches that could better inform future research in this area.

The workshop participants highlighted the need to strengthen the evidence base regarding the mechanisms of action, and the efficacy and effectiveness of meditation for physical and mental health outcomes. It was noted that outcomes of interest would include not only the potential for the prevention of disease and modification of disease course, but also the management of symptoms and promotion of positive health and well-being. The participants also emphasized the need for greater collaboration among research teams, with a goal of improving cross-study comparability.

Specific needs and recommendations that were articulated to enhance further development of the evidence base included investigations in foundational clinical research and translational tools, treatment development studies, and a range of study designs testing efficacy.

  • Foundational clinical research. Foundational research to provide the basic information on which subsequent investigations of efficacy and effectiveness should be built is essential. Such foundational studies must be designed to forecast clinical relevance.
    • Clarify biological mechanisms and pathways by which meditative strategies may impact on health
    • Identify biological measures of the impact of meditation
    • Develop valid, standardized, unbiased, and objective measures and instruments to describe meditative interventions and assess dose effects
    • Develop precise criteria (processes and practices) of intervention fidelity for specific meditation practices
    • Develop indices of expectancy and adherence specific to investigations of meditation practices
  • Treatment development. Studies to develop meditation-based treatments could allow meditation strategies to be optimized for specific health conditions and populations.
    • Develop standardized treatment protocols for specific mental and physical health disorders to improve reproducibility, quality assurance, and cross-study comparability
    • Identify well-characterized patient populations for inclusion in subsequent efficacy studies
    • Develop strategies for monitoring and identifying potential risks and adverse effects
  • Studies to enhance the evidence base for efficacy. A variety of study types and designs are needed to contribute to the evidence base, ranging from retrospective and prospective observational studies to well-designed clinical efficacy investigations. Such studies must be well-controlled and focused, and will further the evidence base for potential clinical applications.
    • Explore opportunities to add measures and gather important descriptive data including recurrent cross-sectional studies such as large national surveys (NHANES, NHIS) and on-going cohort investigations
    • Ensure that studies are sufficiently powered and that the study designs are appropriate to answer the research questions
    • Incorporate inclusion of specific biological and psychological outcomes, with plausible mechanisms linking the specific meditative practice with relevant outcomes
    • Ensure outcomes are clinically significant, measurable, and linked to health importance, including short-term and long-term measures of symptom management, coping with illness, quality of life, prevention of disease, and biological indices of health and disease from multiple systems
    • Develop and incorporate validated and standardized measures of expectancy, treatment adherence, and treatment fidelity for cross-study comparisons. Such cross-study comparisons would be particularly powerful should there be a well-characterized participant specimen repository available for investigations conducted using standardized measures and protocols.
    • Include appropriate control groups that are carefully developed with a consideration of the specific question(s) to be addressed. Factors to be controlled should be specifically identified (e.g., contextual factors not relevant to the specific study hypotheses such as time, attention, built environment, etc)
    • Integrate masking strategies to reduce sources of bias. As with the control group design, such strategies must be developed in light of specific potential sources of bias.

Essential to the success of research to understand and assess the role of meditation for health purposes are focused, effective multidisciplinary and transdisciplinary collaborative teams that incorporate expertise in basic science including cognitive and behavioral neuroscience, translational science, contemplative practices, clinical trials development, medicine, psychology, and biostatistical and trial design strategies and tools.

NCCAM Meditation for Health Purposes

Date: Tuesday, July 8, 2008 to Wednesday, July 9, 2008

The goals of the meeting were to assess current knowledge and identify opportunities for future research on the mechanisms and efficacy of meditation practices for a variety of health concerns. This workshop brought together experts in the fields of meditation practices, research design and methodology, physiological mechanisms, and affective and cognitive processes and outcomes. The meeting drew on this expertise to elucidate relevant aspects that would best move the field of meditation research forward. The meeting utilized a combination of short presentations, discussions, and breakout groups.

NCCAM Grantsmanship Workshop

Date: Tuesday, June 3, 2008 to Thursday, June 5, 2008

The National Center for Complementary and Alternative Medicine (NCCAM), a component of the National Institutes of Health (NIH), conducted a 3-day grantsmanship workshop. This workshop provided researchers, fellows, and graduate students with an in-depth understanding of the NIH grants and review processes, clarify Federal regulations and policies, and highlight areas of special interest and concern.

Emphasis was placed on complementary and alternative medicine (CAM) research. The workshop included time to interact and discuss research ideas with NCCAM staff.

A Public Health Research Agenda for Integrative Medicine

Date: Wednesday, May 14, 2008

The National Center for Complementary and Alternative Medicine presented “A Public Health Research Agenda for Integrative Medicine.” The increasing global use of traditional (e.g., indigenous) complementary and alternative medicine raises important public health questions. Integrative medicine (IM) research has focused primarily on clinical and experimental medicine (safety, efficacy and mechanism of action) and regulatory issues to the general neglect of public health dimensions. A public health research agenda for IM would include a systems approach in considering social, cultural, political, and economic contexts of IM use and outcomes with particular consideration of the needs of high IM users, special groups such as refugees, indigenous peoples, the poor, women users and others, in order to maximize the potential contribution of IM to health care globally. A public health and policy framework for IM has been developed and was presented.

The speaker was Gerard Bodeker, Ed.D., M.Psych., Chair, Global Initiative for Traditional Systems (GIFTS) of Health, Oxford, UK.; Dept of Clinical Medicine, Division of Medical Sciences, University of Oxford, and Oxford Department of International Development, UK; Adjunct Professor of Epidemiology, Mailman School of Public Health, Columbia University. Dr. Bodeker, an Australian whose doctoral studies were at Harvard, holds faculty appointments in public health at Oxford and Columbia Universities. He chaired the Commonwealth Working Group on Traditional, Complementary and Alternative Medicine and advises UN agencies in this field.

The meeting was held on the campus of the National Institutes of Health, 9000 Rockville Pike, Building 50, Room 1328/1334. Seating was limited to approximately the first 60 people. Sign language interpreters were provided.

NIH Videocast