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N C C A M: The National Center for Complementary and Alternative Medicine

At the National Institutes of Health NIH…Turning Discovery Into Health

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Evidence-Based Medicine: Literature Reviews

Evidence-Based Medicine: Literature Reviews

When talking to your patients about CAM, you want to be able to answer the question: Is there any scientific evidence that this CAM product or practice works and is safe? The resources on this page will help inform you about what the science says (limited to the past 5 years).

Açaí

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Acupuncture

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Aging

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Alzheimer's Disease / Dementia

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Antioxidants

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Anxiety

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Arthritis

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Asthma

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Ayurvedic Medicine

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Black Cohosh

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Calcium

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Cancer

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Chamomile

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Chiropractic

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Cholesterol

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Chondroitin and Glucosamine

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Cold and Flu

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Cranberry

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Creatine

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Depression

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Diabetes

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Dietary Supplements and Safety

Literature on Dietary Supplements and Safety (PubMed®)

Echinacea

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Fibromyalgia

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Garlic

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Ginkgo

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Ginseng

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Headache

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Heart Disease

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Hepatitis C

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Hormones

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Hypnosis

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Irritable Bowel Syndrome

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Low Back Pain

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Massage

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Meditation

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Menopause

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Milk Thistle

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Naturopathy

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Pain

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Pediatric Immunization Controversy

Literature on Pediatric Immunization Controversy (PubMed®)

Placebo Effect

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Literature on Placebo Effect (PubMed®)

Post-Traumatic Stress Disorder

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Reservatrol

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Safety and Complementary Therapies

Literature on Safety and Complementary Therapies (PubMed®)

Saw Palmetto

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Sleep Disorders

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Soy

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Spinal Manipulation and Low-Back Pain

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

St. John's Wort

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Tai Chi

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Tea

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)
Herb-Drug Interactions (PubMed®)

Traditional Chinese Medicine

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Vitamin D

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Volatile Oils

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Yoga

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)

Zinc for Common Colds

Systematic Reviews/Reviews/Meta-analysis (PubMed®)
Randomized Controlled Trials (PubMed®)