N C C A M: The National Center for Complementary and Alternative Medicine

At the National Institutes of Health NIH…Turning Discovery Into Health

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Depression

Major depression is a disorder characterized by a depressed mood and/or a loss of interest in nearly all activities consistently for at least 2 weeks. People with major depression may also experience a variety of other symptoms such as loss of appetite, fatigue, sleep disturbance, irritability, difficulty concentrating, and thoughts of death or suicide.